Description

2-Fluoro-5-Methylaniline is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amine group and a fluorine atom on a methyl-substituted benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aniline moiety to modulate bioavailability, metabolic stability, and receptor binding.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental persistence.
• Dye and Pigment Manufacturing: Serves as a building block for producing specialized azo dyes and organic pigments, contributing to color fastness and specific hue properties.
• Liquid Crystal and Electronic Materials: Employed in the synthesis of fluorinated compounds for liquid crystal displays (LCDs) and other electronic applications where specific dielectric and alignment properties are required.
• Polymer Modification: Acts as a monomer or curing agent in the production of specialty polymers, such as polyimides and epoxy resins, to improve thermal stability and chemical resistance.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compounds for various applications.

Basic Information

Product Name	2-Fluoro-5-Methylaniline
CAS No.	452-84-6
Molecular Formula	C7H8FN
Molecular Weight	125.14 g/mol
Synonyms	5-Amino-2-fluorotoluene; 2-Fluoro-5-methylbenzenamine; 2-Fluoro-5-methyl-phenylamine; 5-Methyl-2-fluoroaniline; 2-Fluoro-5-toluidine; 2-Fluoro-5-aminotoluene; 5-Fluoro-2-methylaniline (isomer check); Benzenamine, 2-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylaniline is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to light and tendency for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline mass
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.