Description

2-Chloro-5-Fluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for manufacturers and R&D teams in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and organic pigments.
• Liquid Crystal & OLED Materials: An important building block for creating charge-transport materials and emissive layers in electronic displays.
• Polymer Modification: Used to introduce functional aniline groups into polymer chains to alter thermal or electronic properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Chloro-5-Fluoroaniline
CAS No.	452-83-5
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	5-Fluoro-2-chloroaniline; 2-Chloro-5-fluoro-benzenamine; 1-Amino-2-chloro-5-fluorobenzene; Benzenamine, 2-chloro-5-fluoro-; 2-Chloro-5-fluoro-phenylamine; 2-Chloro-5-fluoroaniline (primary name); 5-Fluoro-o-chloroaniline
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoroaniline is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	28 - 32 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.