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2-Fluoro-4-Methylaniline CAS NO 452-80-2


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CAS No.:452-80-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-4-Methylaniline is a versatile fluorinated aromatic amine building block, essential for synthesizing complex organic molecules. Its value lies in the unique reactivity imparted by the fluorine substituent, which can significantly alter the physical, chemical, and biological properties of final compounds. This intermediate is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating molecules with enhanced metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atom improves efficacy and environmental profile.
  • Dye and Pigment Manufacturing: Serves as a building block for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
  • Liquid Crystal Materials: A valuable intermediate in the production of fluorinated liquid crystals used in advanced display technologies.
  • Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, where it can introduce specific functional groups to modify polymer characteristics.
  • Research & Development: A crucial reagent in academic and industrial R&D labs for exploring new synthetic pathways and fluorine chemistry.

Basic Information

Product Name 2-Fluoro-4-Methylaniline
CAS No. 452-80-2
Molecular Formula C7H8FN
Molecular Weight 125.14 g/mol
Synonyms 2-Fluoro-4-methylbenzenamine; 4-Amino-3-fluorotoluene; 3-Fluoro-4-aminotoluene; 2-Fluoro-p-toluidine; 4-Methyl-2-fluoroaniline; 2-Fluoro-4-methylphenylamine; 3-Fluoro-4-methylaniline; Benzenamine, 2-fluoro-4-methyl-
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Quality Control

Our 2-Fluoro-4-Methylaniline is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of advanced synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or crystalline solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Water Content (KF) ≤0.5%
Related Substances (HPLC) Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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