Description

3-Fluoro-4-Methylphenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a methyl group on the phenol ring, makes it a valuable intermediate for creating molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated monomers and polymers used in liquid crystal displays (LCDs) and other electronic applications.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.
• Polymer Modification: Employed to introduce phenolic and fluorinated functionalities into polymer chains, altering their thermal and chemical resistance.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	3-Fluoro-4-Methylphenol
CAS No.	452-78-8
Molecular Formula	C7H7FO
Molecular Weight	126.13 g/mol
Synonyms	4-Methyl-3-fluorophenol; 3-Fluoro-p-cresol; 3-Fluoro-4-hydroxy-1-methylbenzene; 3-Fluoro-4-hydroxytoluene; 3-Fluoro-4-methyl-1-hydroxybenzene; 3-Fluoro-4-methylphenol; 452-78-8; 3-Fluoro-4-methyl-phenol
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylphenol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.