Description

3-Fluoro-4-Methylaniline is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-donating methyl group and an electron-withdrawing fluorine atom on the aniline ring, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine substituent to improve efficacy and environmental profile.
• Dye and Pigment Manufacturing: Serves as a precursor for specialty dyes, pigments, and optical brighteners, where the fluorine group can alter color fastness and spectral properties.
• Liquid Crystal & Electronic Materials: An important monomer or intermediate in the synthesis of fluorinated liquid crystals and organic semiconductors for display and electronic applications.
• Polymer Modification: Employed to introduce aniline functionality into polymer chains, modifying material properties like adhesion, solubility, and thermal stability.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	3-Fluoro-4-Methylaniline
CAS No.	452-77-7
Molecular Formula	C7H8FN
Molecular Weight	125.14 g/mol
Synonyms	3-Fluoro-p-toluidine; 3-Fluoro-4-methylbenzenamine; 4-Amino-2-fluorotoluene; 2-Fluoro-4-aminotoluene; 3-Fluoro-4-methyl-phenylamine; 4-Methyl-3-fluoroaniline; Benzenamine, 3-fluoro-4-methyl-; 3-Fluoro-4-methyl aniline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylaniline is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full transparency and compliance with your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	40°C - 45°C
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤2.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.