Description

4-Fluoro-2-Methylphenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a methyl group on the phenol ring, makes it a valuable intermediate for creating molecules with tailored properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for fluorinated polymers and liquid crystal materials, improving thermal and chemical resistance.
• Organic Synthesis & Research: A valuable reagent for introducing the 2-methyl-4-fluorophenol moiety into more complex molecules in academic and industrial R&D settings.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and pigments that require fluorinated aromatic components for color fastness.

Basic Information

Product Name	4-Fluoro-2-Methylphenol
CAS No.	452-72-2
Molecular Formula	C7H7FO
Molecular Weight	126.13 g/mol
Synonyms	2-Methyl-4-fluorophenol; 4-Fluoro-o-cresol; 4-Fluoro-2-cresol; 2-Hydroxy-5-fluorotoluene; 5-Fluoro-2-hydroxytoluene; 4-Fluoro-2-methyl-phenol; p-Fluoro-o-cresol; 452-72-2
EINECS	207-207-2

Quality Control

Our 4-Fluoro-2-Methylphenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	32 - 36 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.