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4-Fluoro-2-Methylaniline CAS NO 452-71-1


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CAS No.:452-71-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Fluoro-2-Methylaniline is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amine and a fluorine substituent on the methylated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aniline moiety to modulate bioavailability and metabolic stability.
  • Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental persistence.
  • Dyestuff and Pigment Production: Serves as a building block for creating specialized azo dyes and organic pigments with improved lightfastness and color properties.
  • Liquid Crystal & Electronic Materials: Intermediate in the production of fluorinated compounds for liquid crystal displays (LCDs) and other electronic applications.
  • Polymer Modification: Employed to introduce functional amine and fluorine groups into polymer chains, altering surface properties and chemical resistance.
  • Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name 4-Fluoro-2-Methylaniline
CAS No. 452-71-1
Molecular Formula C7H8FN
Molecular Weight 125.15 g/mol
Synonyms 2-Methyl-4-fluoroaniline; 4-Fluoro-o-toluidine; 4-Fluoro-2-methylbenzenamine; 2-Amino-5-fluorotoluene; 5-Fluoro-2-methylaniline; 4-Fluoro-2-toluidine; 2-Methyl-4-fluorobenzenamine; 4-Fluoro-2-methylphenylamine
EINECS 207-207-3

Quality Control

Our 4-Fluoro-2-Methylaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item Specification
Appearance Clear, pale yellow to brown liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Related Substances (HPLC) Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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