Description

1H-Pyrrolo[3,2-D]Pyrimidine (8Ci,9Ci) is a high-value heterocyclic aromatic compound that serves as a critical building block in advanced organic synthesis. Its fused pyrrolopyrimidine core is a privileged scaffold for designing novel bioactive molecules, making it indispensable for pharmaceutical research and development. This intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Core scaffold for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Key precursor in developing new fungicides, herbicides, and plant growth regulators.
• Material Science: Building block for organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology: Used in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Fundamental research reagent in heterocyclic and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	1H-Pyrrolo[3,2-D]Pyrimidine (8Ci,9Ci)
CAS No.	452-20-0
Molecular Formula	C6H5N3
Molecular Weight	119.12 g/mol
Synonyms	1H-Pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine; 7-Azaindole; 1-Deazapurine; 1H-7-Azaindole; 7-Aza-1H-indole; NSC 51143; 452-20-0
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.