Description

3-Fluoro-4-Methoxyphenol is a versatile fluorinated phenolic compound with the CAS number 452-11-9. This high-purity intermediate is valued for its unique chemical structure, which enables precise molecular modifications in advanced synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies, contributing to improved performance and durability.
• Polymer & Resin Modifier: Incorporated to impart specific properties like enhanced thermal stability, chemical resistance, or adhesion in specialty polymers and epoxy resins.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex, high-value dyes and pigments where fluorine substitution can alter color fastness and spectral properties.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures.

Basic Information

Product Name	3-Fluoro-4-Methoxyphenol
CAS No.	452-11-9
Molecular Formula	C7H7FO2
Molecular Weight	142.13 g/mol
Synonyms	4-Methoxy-3-fluorophenol; 3-Fluoro-4-hydroxyanisole; 3-Fluoro-p-hydroxyanisole; 3-Fluoro-4-methoxy-1-hydroxybenzene; 1-Fluoro-2-methoxy-4-hydroxybenzene; Phenol, 3-fluoro-4-methoxy-; FMP (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Methoxyphenol is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.