Description

2,4-Difluorobenzyl Chloride is a versatile and highly reactive organofluorine building block essential for advanced chemical synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which significantly influences the electronic properties and metabolic stability of final target molecules. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzyl moiety to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved pesticidal activity and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in advanced display technologies.
• Organic Synthesis Reagent: Employed in nucleophilic substitution reactions to introduce the benzyl chloride functional group into more complex molecular architectures.
• Polymer Modification: Acts as a monomer or cross-linking agent in the production of specialty polymers with unique thermal and chemical resistance properties.
• Material Science Research: Utilized in creating novel organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	2,4-Difluorobenzyl Chloride
CAS No.	452-07-3
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	α-Chloro-2,4-difluorotoluene; (2,4-Difluorophenyl)methyl Chloride; 2,4-Difluoro-α-chlorotoluene; 2,4-Difluorobenzylchloride; 1-(Chloromethyl)-2,4-difluorobenzene; Benzene, 1-(chloromethyl)-2,4-difluoro-; 2,4-DFBC
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobenzyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC/HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.