Description

Benzenemethanol, 4-Fluoro-A-[(Methylamino)Methyl]- is a specialized fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. This chemical matters because it provides a versatile scaffold for introducing both fluorine and a functionalized amine side chain, enabling the development of novel molecules with tailored properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Fluorine Chemistry Studies: Employed in academic and industrial research to explore structure-activity relationships (SAR) in fluorinated compounds.
• Fine Chemical Production: Manufactured as a high-purity intermediate for custom synthesis projects requiring specific fluorinated benzylamine structures.

Basic Information

Product Name	Benzenemethanol, 4-Fluoro-A-[(Methylamino)Methyl]-
CAS No.	451-45-6
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	4-Fluoro-α-[(methylamino)methyl]benzenemethanol; 1-(4-Fluorophenyl)-2-(methylamino)ethanol; Norfenefrine Impurity; 4-Fluoronorephedrine; 2-(Methylamino)-1-(4-fluorophenyl)ethanol; α-[(Methylamino)methyl]-4-fluorobenzenemethanol; 4-Fluoro-N-methylephedrine; 4-Fluoro-N-methylpseudoephedrine
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, 4-Fluoro-A-[(Methylamino)Methyl]- adheres to strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality system is designed to support cGMP compliance for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.