Description

[1,1'-Biphenyl]-4-Amine, 3-(Trifluoromethyl)- is a high-purity aromatic amine derivative featuring a biphenyl core substituted with an amino group and a trifluoromethyl group. This compound is a critical advanced pharmaceutical intermediate and building block valued for its ability to impart unique physicochemical properties to target molecules. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the manufacture of electronic chemicals for display technologies, contributing to charge transport and molecular alignment.
• Polymer & Resin Modifier: Acts as a monomer or curing agent to create specialty polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a ligand precursor in catalytic systems.
• Dye & Pigment Precursor: Employed in the synthesis of high-performance dyes and pigments for specialized industrial applications.

Basic Information

Product Name	[1,1'-Biphenyl]-4-Amine, 3-(Trifluoromethyl)-
CAS No.	449-42-3
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	3-(Trifluoromethyl)[1,1'-biphenyl]-4-amine; 4-Amino-3'-trifluoromethylbiphenyl; 3'-Trifluoromethyl-4-aminobiphenyl; 3-(Trifluoromethyl)biphenyl-4-amine; 3-Trifluoromethyl-4-aminobiphenyl; 3'-Trifluoromethylbiphenyl-4-ylamine; 4-Amino-3'-(trifluoromethyl)biphenyl; Biphenyl-4-amine, 3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-4-Amine, 3-(Trifluoromethyl)- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.