Description

4-Fluorophenylglyoxal Hydrate is a versatile fluorinated aromatic glyoxal derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactive diketone functionality, which enables the construction of complex heterocyclic scaffolds and fine chemical intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for heterocycles like imidazoles, quinoxalines, and fused ring systems.
• Agrochemical Synthesis: Used in developing novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity, stability, and metabolic properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Cross-Coupling & Condensation Reactions: Acts as an electrophilic coupling partner in reactions to form carbon-carbon and carbon-heteroatom bonds.

Basic Information

Product Name	4-Fluorophenylglyoxal Hydrate
CAS No.	447-43-8
Molecular Formula	C8H7FO3 • xH2O
Molecular Weight	182.14 g/mol (Anhydrous basis)
Synonyms	2-Oxo-2-(4-fluorophenyl)acetaldehyde Hydrate; (4-Fluorophenyl)glyoxal Hydrate; 4-Fluorobenzoylcarboxaldehyde Hydrate; 4-Fluorophenyl-α-oxoacetaldehyde Hydrate; 4-Fluorobenzoylformaldehyde Hydrate; p-Fluorophenylglyoxal Hydrate; 4-Fluorophenyl-1,2-dione Hydrate; α-Oxo-4-fluorobenzeneacetaldehyde Hydrate
EINECS	Contact for details

Quality Control

Our 4-Fluorophenylglyoxal Hydrate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as an easily oxidized compound, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.