Description

5-Fluoro-2-Nitrophenol is a versatile halogenated nitrophenol derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of its electron-withdrawing nitro and fluoro groups on the aromatic ring, enabling precise electrophilic substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a high-purity building block for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antibacterial and anticancer agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, pesticides, and fungicides that leverage the bioactivity of the fluoronitrophenol structure.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and pigments where the fluorine atom enhances lightfastness and alters color properties.
• Liquid Crystal & Electronic Materials: Intermediate for synthesizing fluorinated compounds used in liquid crystal displays (LCDs) and organic electronic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic synthesis, particularly in studies involving regioselective aromatic substitution.
• Complex Ligand Synthesis: Starting material for creating fluorinated ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	5-Fluoro-2-Nitrophenol
CAS No.	446-36-6
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	2-Nitro-5-fluorophenol; 5-Fluoro-2-nitrophenol; 2-Nitro-5-fluorophenol; 5-Fluor-2-nitrophenol; 5-Fluoro-2-hydroxy-nitrobenzene; Phenol, 5-fluoro-2-nitro-; NSC 403119; 5-Fluoro-2-nitrophenolate
EINECS	207-173-5

Quality Control

Our 5-Fluoro-2-Nitrophenol is manufactured under a strict quality management system. We provide material that meets high-purity standards suitable for research and industrial synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.