Description

4-Amino-2-Fluoro-5-Nitroanisole, also known as 5-Fluoro-4-Methoxy-2-Nitroaniline, is a high-value aromatic amine derivative and a key fluorinated organic intermediate. Its molecular structure, featuring amino, fluoro, nitro, and methoxy substituents, makes it an essential building block for synthesizing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of advanced active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drugs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a key intermediate for producing specialized azo dyes and pigments, contributing to color fastness and unique hue properties.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Liquid Crystal (LC) and Electronic Chemicals: Employed in the synthesis of fluorinated liquid crystal compounds for high-performance displays.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	4-Amino-2-Fluoro-5-Nitroanisole
CAS No.	446-20-8
Molecular Formula	C7H7FN2O3
Molecular Weight	186.14 g/mol
Synonyms	5-Fluoro-4-Methoxy-2-Nitroaniline; 2-Fluoro-4-Methoxy-5-Nitroaniline; 2-Amino-4-Fluoro-5-Nitroanisole; 4-Methoxy-2-Nitro-5-Fluoroaniline; 5-Fluoro-2-Nitro-4-Methoxyaniline; 4-Amino-2-Fluoro-5-Nitro-1-Methoxybenzene; 2-Nitro-5-Fluoro-4-Methoxyaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Fluoro-5-Nitroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key specifications such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. Due to its light-sensitive and potentially hygroscopic nature, containers should be kept sealed under an inert atmosphere for long-term storage to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.