Description

4-Amino-3,5-Dinitrobenzotrifluoride is a high-value, multi-functional aromatic intermediate characterized by its unique combination of amino, nitro, and trifluoromethyl substituents. This compound is essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where the introduction of electron-withdrawing groups and fluorine atoms is required. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic cores for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group contributes to lipophilicity and membrane penetration.
• Dye and Pigment Manufacturing: Serves as a precursor for high-performance, light-fast azo dyes and pigments used in specialized industrial applications.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic structure.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.

Basic Information

Product Name	4-Amino-3,5-Dinitrobenzotrifluoride
CAS No.	445-66-9
Molecular Formula	C7H4F3N3O4
Molecular Weight	251.12 g/mol
Synonyms	2-Amino-4,6-dinitrobenzotrifluoride; 3,5-Dinitro-4-aminobenzotrifluoride; 4-Amino-3,5-dinitro-α,α,α-trifluorotoluene; 2-Trifluoromethyl-4,6-dinitroaniline; Benzene, 2-amino-1,3-dinitro-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2,4-dinitroaniline; 2,4-Dinitro-5-(trifluoromethyl)aniline; 4,6-Dinitro-2-(trifluoromethyl)aniline
EINECS	Contact for details

Quality Control

Our 4-Amino-3,5-Dinitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.