Description

2-Amino-4-Chlorobenzotrifluoride is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its trifluoromethyl and chloro substituents impart unique electronic and steric properties, making it a valuable intermediate for creating high-performance molecules. This compound is essential for R&D and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for specialty chemicals used in electronic displays and organic light-emitting diodes due to its electron-withdrawing characteristics.
• Dye & Pigment Manufacturing: Employed in the production of high-value, light-fast dyes and pigments for industrial and specialty applications.
• Polymer & Resin Modifier: Acts as a monomer or additive to introduce fluorine-containing groups into polymers, improving their chemical resistance and thermal stability.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel fluorinated compounds.

Basic Information

Product Name	2-Amino-4-Chlorobenzotrifluoride
CAS No.	445-14-7
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)aniline; 2-Amino-4-chloro-α,α,α-trifluorotoluene; 4-Chloro-α,α,α-trifluoro-o-toluidine; 2-Trifluoromethyl-4-chloroaniline; Benzenamine, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-2-trifluoromethylaniline; 2-Amino-4-chlorobenzotrifluoride; 4-Chloro-2-aminobenzotrifluoride
EINECS	207-169-5

Quality Control

Our 2-Amino-4-Chlorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	44 - 48 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.