Description

4-Amino-2-Chlorobenzotrifluoride is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and chloro substituents on the aromatic ring make it a high-value intermediate for creating compounds with enhanced biological activity and material properties. This chemical is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to improved efficacy and environmental stability.
• Dye and Pigment Manufacturing: Serves as a starting material for producing high-performance, light-fast azo dyes and complex organic pigments.
• Liquid Crystal & OLED Materials: An important intermediate for creating fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers with specific thermal and chemical resistance properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research to explore new molecular entities and functional materials.

Basic Information

Product Name	4-Amino-2-Chlorobenzotrifluoride
CAS No.	445-13-6
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Chloro-4-aminobenzotrifluoride; 2-Chloro-α,α,α-trifluoro-p-toluidine; 4-Amino-2-chloro-α,α,α-trifluorotoluene; 2-Chloro-4-(trifluoromethyl)aniline; 2-Chloro-α,α,α-trifluoro-4-methylaniline; Benzenamine, 2-chloro-4-(trifluoromethyl)-; p-Amino-o-chlorobenzotrifluoride
EINECS	207-165-6

Quality Control

Our 4-Amino-2-Chlorobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.