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4-Amino-3-(Trifluoromethyl)Phenol CAS NO 445-04-5


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CAS No.:445-04-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Amino-3-(Trifluoromethyl)Phenol is a versatile aromatic compound featuring both an amino and a trifluoromethyl group on the phenol ring. This unique structure makes it a valuable pharmaceutical intermediate and a key building block in the synthesis of more complex molecules. It is primarily utilized by agrochemical and pharmaceutical research and manufacturing sectors for developing active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylated aromatic core.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and stability.
  • Dye and Pigment Manufacturing: Serves as a building block for specialty dyes and organic pigments due to its aromatic amine functionality.
  • Liquid Crystal Materials: Employed in the research and development of fluorinated compounds for electronic display applications.
  • Polymer Modification: Acts as a monomer or additive to introduce specific properties like hydrophobicity or chemical resistance into polymer chains.
  • Organic Synthesis & Research: A valuable reagent for academic and industrial R&D laboratories exploring novel fluorinated compounds and their reactivities.

Basic Information

Product Name 4-Amino-3-(Trifluoromethyl)Phenol
CAS No. 445-04-5
Molecular Formula C7H6F3NO
Molecular Weight 177.12 g/mol
Synonyms 3-(Trifluoromethyl)-4-aminophenol; 4-Amino-α,α,α-trifluoro-m-cresol; 5-Amino-2-hydroxybenzotrifluoride; 2-Hydroxy-5-aminobenzotrifluoride; 4-Amino-3-trifluoromethylphenol; 4-Amino-α,α,α-trifluoro-3-methylphenol; 3-Trifluoromethyl-4-aminophenol; 5-Amino-2-(trifluoromethyl)phenol
EINECS 207-161-3

Quality Control

Our 4-Amino-3-(Trifluoromethyl)Phenol is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 118 - 122 °C
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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