Description

2-Amino-5-Bromobenzotrifluoride is a high-purity, multi-functional aromatic amine building block characterized by its bromine and trifluoromethyl substituents. This compound is valued for its role as a critical intermediate in advanced organic synthesis, enabling the introduction of both halogen and fluorine-containing groups into target molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and charge-generating compounds in electronic displays and organic light-emitting diodes.
• Polymer & Dye Chemistry: Employed in the synthesis of specialty polymers, dyes, and pigments, imparting unique solubility and color-fastness properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial research in medicinal chemistry and material science exploration.

Basic Information

Product Name	2-Amino-5-Bromobenzotrifluoride
CAS No.	445-02-3
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	5-Bromo-2-aminobenzotrifluoride; 2-Amino-5-bromo-α,α,α-trifluorotoluene; 5-Bromo-2-(trifluoromethyl)aniline; 2-(Trifluoromethyl)-5-bromoaniline; 5-Bromo-α,α,α-trifluoro-o-toluidine; 5-Bromo-2-trifluoromethylaniline; 2-Amino-α,α,α-trifluoro-5-bromotoluene; 5-Bromo-2-aminotrifluorotoluene
EINECS	207-161-5

Quality Control

Our 2-Amino-5-Bromobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.