Description

2-Bromo-4,6-Difluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and pesticides, where the difluoroaniline core contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for electronic chemicals used in display technologies and organic light-emitting diodes.
• Dyestuff & Pigment Manufacturing: Employed in the production of specialized dyes and pigments, leveraging the aniline functionality for color development.
• Polymer Modification: Acts as a monomer or additive to introduce halogenated aromatic groups into polymer chains, altering material properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for constructing biaryl systems.

Basic Information

Product Name	2-Bromo-4,6-Difluoroaniline
CAS No.	444-14-4
Molecular Formula	C6H4BrF2N
Molecular Weight	208.00 g/mol
Synonyms	2-Bromo-4,6-difluoroaniline; 4,6-Difluoro-2-bromoaniline; 2-Bromo-4,6-difluorobenzenamine; Benzenamine, 2-bromo-4,6-difluoro-; Aniline, 2-bromo-4,6-difluoro-; 444-14-4; 2-Br-4,6-F2-C6H2NH2
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,6-Difluoroaniline is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.