Description

2,3,4,5,6-Pentafluorobenzyl Alcohol is a high-value, multi-fluorinated aromatic building block. This compound matters for its unique reactivity profile, serving as a versatile precursor for introducing the pentafluorobenzyl group into complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination to modify solubility, stability, and biological activity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorination improves efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Derivatization Agent in Analytical Chemistry: Employed in GC/MS and HPLC for labeling and detecting sensitive analytes, enhancing detection limits and selectivity.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and low dielectric constants.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating complex fluorinated aromatic systems.

Basic Information

Product Name	2,3,4,5,6-Pentafluorobenzyl Alcohol
CAS No.	440-60-8
Molecular Formula	C7H3F5O
Molecular Weight	198.09 g/mol
Synonyms	Pentafluorobenzyl Alcohol; (Pentafluorophenyl)methanol; α,α,α,2,3,4,5,6-Heptafluorotoluene (reduction product); Perfluorobenzyl Alcohol; 2,3,4,5,6-Pentafluorobenzenemethanol; PFB Alcohol; PFBA; Benzyl alcohol, 2,3,4,5,6-pentafluoro-
EINECS	207-128-4

Quality Control

Our 2,3,4,5,6-Pentafluorobenzyl Alcohol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This product is easily oxidized and should be stored under an inert atmosphere (nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.