Description

Phenprocoumon CAS NO 435-97-2 is a synthetic 4-hydroxycoumarin derivative and a potent anticoagulant agent. It functions as a vitamin K antagonist, effectively inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. This compound is primarily utilized as a key active pharmaceutical ingredient (API) in the development and production of anticoagulant medications for the prevention and treatment of thromboembolic disorders. Its reliable mechanism of action makes it a critical component for pharmaceutical manufacturers and research institutions focused on cardiovascular health.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of oral anticoagulant medications for long-term therapy.
• Thrombosis Prevention: Used in drugs to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE).
• Stroke and Systemic Embolism Prevention: A key component in treatments for patients with atrial fibrillation or prosthetic heart valves.
• Pharmaceutical Research & Development: Serves as a reference standard and a lead compound in the discovery of new anticoagulant therapies.
• Biochemical Research: Employed in studies investigating the vitamin K cycle, blood coagulation pathways, and enzyme inhibition mechanisms.

Basic Information

Product Name	Phenprocoumon
CAS No.	435-97-2
Molecular Formula	C18H16O3
Molecular Weight	280.32 g/mol
Synonyms	Phenprocoumon; 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one; Marcoumar; Liquamar; Phenprocoumonum; Phenprocoumone; 3-(1-Phenylpropyl)-4-hydroxycoumarin; Falirom
EINECS	207-123-7

Quality Control

Our Phenprocoumon is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other pharmacopeial methods. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.