Description

2-Amino-6-Chlorobenzotrifluoride is a versatile aromatic amine building block characterized by its trifluoromethyl and chloro substituents, which impart unique electronic and steric properties. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure enables the fine-tuning of biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development teams in the life sciences and specialty chemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in electronic displays and devices.
• Dye & Pigment Manufacturing: Employed in the production of high-performance, light-fast dyes and pigments for industrial applications.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into specialty polymers.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel chemical entities in academic and industrial labs.

Basic Information

Product Name	2-Amino-6-Chlorobenzotrifluoride
CAS No.	432-21-3
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	6-Chloro-2-aminobenzotrifluoride; 2-Amino-α,α,α-trifluoro-6-chlorotoluene; 2-Chloro-6-aminobenzotrifluoride; 1-Chloro-3-amino-4-(trifluoromethyl)benzene; 2-Chloro-6-(trifluoromethyl)aniline; Benzenamine, 2-chloro-6-(trifluoromethyl)-; 6-Chloro-2-(trifluoromethyl)aniline; 2-Chloro-α,α,α-trifluoro-m-toluidine
EINECS	207-088-1

Quality Control

Our 2-Amino-6-Chlorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.