Description

4-Fluorophenyl Acetate is a versatile fluorinated aromatic ester, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the introduction of both the fluorophenyl moiety and an acetyl group, enabling precise structural modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic rings to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorinated phenyl acetate groups into polymer chains, altering physical properties like solubility, thermal stability, and surface energy.
• Organic Synthesis Reagent: Acts as an acetylating agent or a protected form of 4-fluorophenol in multi-step synthetic routes for complex molecules.
• Dye & Pigment Intermediate: Utilized in the manufacture of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	4-Fluorophenyl Acetate
CAS No.	405-51-6
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	p-Fluorophenyl Acetate; 1-Acetoxy-4-fluorobenzene; 4-Fluorophenyl ethanoate; 4-Fluoro-1-acetoxybenzene; Acetic Acid 4-Fluorophenyl Ester; p-Fluorphenylacetat; 4-Fluorphenylacetat; (4-Fluorophenyl) acetate
EINECS	206-973-4

Quality Control

Our 4-Fluorophenyl Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.