Description

2-Fluoro-4-Methoxybenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the synergistic reactivity of the benzyl alcohol group and the strategic fluorine substitution on the methoxy-substituted benzene ring, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to introduce fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom improves biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The benzyl alcohol moiety can be functionalized or used in palladium-catalyzed coupling reactions to build complex aromatic systems.
• Protecting Group Chemistry: Can be utilized in multi-step syntheses where selective protection and deprotection are required.

Basic Information

Product Name	2-Fluoro-4-Methoxybenzyl Alcohol
CAS No.	405-09-4
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	(2-Fluoro-4-methoxyphenyl)methanol; 4-Methoxy-2-fluorobenzyl alcohol; 2-Fluoro-4-methoxybenzenemethanol; 2-Fluoro-p-anisyl alcohol; α-Hydroxy-2-fluoro-4-methoxytoluene; 2-Fluoro-4-methoxybenzylalcohol; 405-09-4; 2-Fluoro-4-methoxy-phenyl-methanol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methoxybenzyl Alcohol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the exacting standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.