Description

3,5-Difluoro-n-(4-Fluorophenyl)Aniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique trifluoro-substituted aromatic structure, which imparts desirable electronic and steric properties to target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display materials and organic light-emitting diodes.
• Polymer Chemistry: Monomer for creating specialty polymers with improved thermal stability, chemical resistance, and unique optical properties.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to construct complex biaryl systems.
• Dye & Pigment Manufacturing: Intermediate for synthesizing high-performance, light-fast fluorinated dyes and pigments.

Basic Information

Product Name	3,5-Difluoro-n-(4-Fluorophenyl)Aniline
CAS No.	403-80-5
Molecular Formula	C12H8F3N
Molecular Weight	223.20 g/mol
Synonyms	3,5-Difluoro-4'-fluoroaniline; Benzenamine, 3,5-difluoro-N-(4-fluorophenyl)-; N-(4-Fluorophenyl)-3,5-difluoroaniline; 4'-Fluoro-3,5-difluoroaniline; 3,5-Difluoro-4-fluoroaniline; 3,5,4'-Trifluorodiphenylamine; (4-Fluorophenyl)(3,5-difluorophenyl)amine
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-n-(4-Fluorophenyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.