Description

2-Nitro-5-(Trifluoromethyl)Phenol is a versatile aromatic compound featuring both nitro and trifluoromethyl substituents on the phenol ring. This unique structure makes it a valuable advanced intermediate for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams for applications in medicinal chemistry and crop protection research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups contribute to biological activity.
• Dye and Pigment Precursor: Serves as an intermediate in the production of specialized dyes and pigments for industrial applications.
• Liquid Crystal Materials: Can be utilized in the synthesis of fluorinated compounds for electronic displays and advanced material science.
• Organic Synthesis & Research: A valuable reagent for academic and industrial research in organic chemistry, particularly in reactions involving electrophilic aromatic substitution and further functionalization.

Basic Information

Product Name	2-Nitro-5-(Trifluoromethyl)Phenol
CAS No.	402-17-5
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	5-(Trifluoromethyl)-2-nitrophenol; 2-Hydroxy-5-(trifluoromethyl)nitrobenzene; 2-Nitro-α,α,α-trifluoro-p-cresol; Phenol, 2-nitro-5-(trifluoromethyl)-; NSC 404080; 5-Trifluoromethyl-2-nitrophenol
EINECS	206-938-8

Quality Control

Our 2-Nitro-5-(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.