Description

3-Amino-4-Nitrobenzotrifluoride is a versatile fluorinated aromatic intermediate of significant commercial importance. Its unique structure, featuring both an amino and a nitro group on a trifluoromethyl-substituted benzene ring, makes it a critical building block for advanced synthesis. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a building block for high-performance, light-fast organic dyes and pigments used in textiles and coatings.
• Liquid Crystal & OLED Materials: A crucial intermediate for synthesizing fluorinated compounds used in electronic display technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Amino-4-Nitrobenzotrifluoride
CAS No.	402-14-2
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	3-Amino-4-nitro-α,α,α-trifluorotoluene; 2-Nitro-5-(trifluoromethyl)aniline; 4-Nitro-3-aminobenzotrifluoride; 5-Amino-2-nitrobenzotrifluoride; Benzenamine, 2-nitro-5-(trifluoromethyl)-; α,α,α-Trifluoro-3-amino-4-nitrotoluene; 3-Amino-4-nitro-α,α,α-trifluoromethylbenzene
EINECS	206-938-9

Quality Control

Our 3-Amino-4-Nitrobenzotrifluoride is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.