Description

2-Bromo-5-Trifluoromethylphenol is a versatile halogenated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and trifluoromethyl substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the phenol and halogen groups.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes due to its aromatic and halogenated structure.
• Polymer Modification: Acts as a monomer or additive for creating specialty polymers with enhanced flame retardancy, stability, or specific functional groups.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce complex aromatic units.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing specialized dyes and pigments with unique color and fastness properties.

Basic Information

Product Name	2-Bromo-5-Trifluoromethylphenol
CAS No.	402-05-1
Molecular Formula	C7H4BrF3O
Molecular Weight	241.01 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-p-cresol; 5-Trifluoromethyl-2-bromophenol; 2-Bromo-5-(trifluoromethyl)phenol; Phenol, 2-bromo-5-(trifluoromethyl)-; 3-Bromo-4-hydroxybenzotrifluoride; 4-Hydroxy-3-bromobenzotrifluoride; NSC 404087; 2-Bromo-α,α,α-trifluoro-4-hydroxybenzene
EINECS	206-935-3

Quality Control

Our 2-Bromo-5-Trifluoromethylphenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring reliable supply and traceability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.