Description

3-Amino-5-Nitrobenzotrifluoride is a high-value aromatic amine derivative containing both nitro and trifluoromethyl functional groups, making it a versatile and reactive building block for advanced synthesis. Its unique structure is critical for introducing specific electronic and steric properties into target molecules, enabling the development of compounds with enhanced performance characteristics. This intermediate is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries seeking to innovate in areas like crop protection and active pharmaceutical ingredient (API) development.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, pesticides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for creating molecules with specific receptor-binding profiles.
• Dye and Pigment Synthesis: Serves as an intermediate for producing specialized azo dyes and organic pigments, where the amino and nitro groups contribute to color formation and fastness properties.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl amines.

Basic Information

Product Name	3-Amino-5-Nitrobenzotrifluoride
CAS No.	401-94-5
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	5-Nitro-3-(trifluoromethyl)aniline; 3-Trifluoromethyl-5-nitroaniline; 1-Amino-3-nitro-5-(trifluoromethyl)benzene; 3-Amino-5-nitro-α,α,α-trifluorotoluene; Benzenamine, 3-nitro-5-(trifluoromethyl)-; 3-(Trifluoromethyl)-5-nitroaniline; 5-Nitro-α,α,α-trifluoro-m-toluidine
EINECS	206-937-5

Quality Control

Our 3-Amino-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.