Description

2-Amino-3-Chloro-5-Nitrobenzotrifluoride is a high-value trifluoromethylated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring amino, chloro, nitro, and trifluoromethyl substituents, makes it indispensable for creating complex, functional molecules with tailored properties. This intermediate is primarily sought after by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions engaged in material science and dye chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a building block for producing high-performance, light-fast organic dyes and pigments.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic chemistry, facilitating the exploration of new synthetic pathways.

Basic Information

Product Name	2-Amino-3-Chloro-5-Nitrobenzotrifluoride
CAS No.	400-67-9
Molecular Formula	C7H4ClF3N2O2
Molecular Weight	240.57 g/mol
Synonyms	2-Amino-3-chloro-5-nitrobenzotrifluoride; 3-Chloro-2-amino-5-nitrobenzotrifluoride; 2-Amino-3-chloro-5-nitro-α,α,α-trifluorotoluene; 2-Chloro-6-nitro-α,α,α-trifluoro-m-toluidine; 3-Chloro-5-nitro-2-(trifluoromethyl)aniline; 2-(Trifluoromethyl)-3-chloro-5-nitroaniline; Benzene, 2-amino-3-chloro-5-nitro-α,α,α-trifluoro-; 400-67-9
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	98 - 102 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.