Description

2-Hydroxybenzotrifluoride is a versatile fluorinated aromatic building block, also known by its CAS number 44-30-4. This compound is valued for its unique combination of a phenolic hydroxyl group and a trifluoromethyl substituent, which imparts enhanced lipophilicity and metabolic stability to target molecules. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for synthesizing advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in anti-inflammatory, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display and lighting applications.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Acts as a versatile starting material or protecting group in complex multi-step organic syntheses within fine chemical production.

Basic Information

Product Name	2-Hydroxybenzotrifluoride
CAS No.	44-30-4
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	2-(Trifluoromethyl)phenol; α,α,α-Trifluoro-o-cresol; o-Hydroxybenzotrifluoride; 2-Trifluoromethylphenol; o-Trifluoromethylphenol; 2-Cresol, α,α,α-trifluoro-; Phenol, 2-(trifluoromethyl)-
EINECS	247-598-7

Quality Control

Our 2-Hydroxybenzotrifluoride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment upon request, providing full traceability and compliance assurance for your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 15-25°C. The product is compatible with most common organic solvents but should be kept in its original container to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.