Description

3-Bromo-2,6-Difluorobenzaldehyde is a versatile and high-purity fluorinated aromatic aldehyde building block. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and fluorinated motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, due to the influence of the fluorine and bromine substituents on bioavailability and metabolic stability.
• Agrochemical Active Ingredient Development: Used in creating novel herbicides, fungicides, and insecticides where the difluoro and bromo groups can enhance biological activity and environmental persistence profiles.
• Ligand and Catalyst Synthesis: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals, where fluorinated aromatics are critical for tuning electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients with specific molecular requirements.

Basic Information

Product Name	3-Bromo-2,6-Difluorobenzaldehyde
CAS No.	398456-82-1
Molecular Formula	C7H3BrF2O
Molecular Weight	221.00 g/mol
Synonyms	2,6-Difluoro-3-bromobenzaldehyde; 3-Bromo-2,6-difluorobenzenecarboxaldehyde; Benzaldehyde, 3-bromo-2,6-difluoro-; 398456-82-1; 3-Br-2,6-F2-C6H2CHO
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,6-Difluorobenzaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and guarantee consistent high purity to meet the stringent requirements of research and scale-up processes. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and GC-MS is supplied with each shipment to ensure quality assurance and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.