Description

Stresscopin-Related Peptide (6-43) (Human) Trifluoroacetate Salt is a synthetic peptide fragment corresponding to amino acids 6-43 of the human stresscopin (Urocortin III) protein. This high-purity peptide is a critical research tool for investigating the urocortin system, which plays a significant role in the body's stress response, energy homeostasis, and cardiovascular function. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, neuroscience, and metabolic disorder research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the CRF (corticotropin-releasing factor) receptor system, specifically the CRF-R2 receptor.
• Pharmacological Assay Development: Serves as a key ligand in competitive binding assays and functional cellular assays to screen for novel therapeutics targeting stress-related pathways.
• Endocrinology Studies: Essential for investigating the physiological roles of stresscopin/urocortin III in appetite regulation, anxiety, and cardiovascular function.
• Antibody Production & Validation: Acts as an immunogen for generating specific antibodies or as a coating antigen in immunoassay development (e.g., ELISA).
• Cell Signaling Research: Applied in studies to elucidate intracellular signaling cascades activated by CRF-R2 receptor binding.
• Quality Control Reference: Employed as an analytical standard in the quality control of related peptide-based pharmaceuticals or research reagents.

Basic Information

Product Name	Stresscopin-Related Peptide (6-43) (Human) Trifluoroacetate Salt
CAS No.	398001-88-2
Molecular Formula	C185H295N55O52 • xC2HF3O2
Molecular Weight	~4200 g/mol (Free base)
Synonyms	Urocortin III (6-43) (human); hUCN3 (6-43); Stresscopin (6-43); SCP (6-43); CRF-R2 Ligand Fragment; Corticotropin-Releasing Factor Related Peptide; TFA Salt of Stresscopin-Related Peptide
EINECS	Contact for details

Quality Control

Our Stresscopin-Related Peptide (6-43) is manufactured under stringent conditions to ensure the highest standards of purity and consistency. Each batch is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, identity, and content specifications. We adhere to GMP principles for research-grade materials to guarantee reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Trifluoroacetate Content (HPLC)	≤ 15%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.