Description

Mca-Arg-Pro-Lys-Pro-Gln-Oh is a synthetic, modified peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound, identified by CAS No. 396718-26-6, is valued for its role as a specific substrate or inhibitor in enzymatic studies, particularly those involving proteases. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on metabolic pathways, signal transduction, and novel therapeutic agent discovery.

Application

• Biochemical Research: Used as a specialized substrate for studying the activity and kinetics of specific proteolytic enzymes.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of peptide-based drugs and diagnostic agents.
• Enzyme Inhibition Studies: Acts as a potent and selective inhibitor to probe the function of target enzymes in complex biological systems.
• Cell Signaling Pathway Analysis: Employed in assays to investigate intracellular signaling cascades and protein-protein interactions.
• Proteomics: Utilized as a tool peptide for mass spectrometry calibration and method development in protein identification workflows.
• Academic Research: Fundamental tool for universities and research labs exploring peptide chemistry, enzymology, and molecular biology.

Basic Information

Product Name	Mca-Arg-Pro-Lys-Pro-Gln-Oh
CAS No.	396718-26-6
Molecular Formula	C41H62N12O11
Molecular Weight	875.0 g/mol (approx.)
Synonyms	7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Gln-OH; Mca-RPKPQ-OH; Fluorogenic Peptide Substrate Mca-RPKPQ; (7-Methoxycoumarin-4-yl)acetyl-Arg-Pro-Lys-Pro-Gln; MMP Substrate; FRET Peptide; Peptide for Protease Assay; Mca-Arg-Pro-Lys-Pro-Glutamine
EINECS	Contact for details

Quality Control

Our Mca-Arg-Pro-Lys-Pro-Gln-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.