Description

4-[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl]Oxy-3,5-Dimethyl-Benzonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role in the synthesis of targeted therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to develop novel drug candidates with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the development of chemotherapeutic agents and compounds for cancer treatment studies.
• Antiviral Drug Development: Serves as a building block for creating potential antiviral medications.
• Biochemical Research: Employed in academic and industrial labs for studying enzyme inhibition and signal transduction pathways.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to create complex molecules for various high-value applications.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl]Oxy-3,5-Dimethyl-Benzonitrile
CAS No.	394729-17-0
Molecular Formula	C20H16BrN7O
Molecular Weight	450.30 g/mol
Synonyms	4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile; 3,5-Dimethyl-4-((5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)benzonitrile; 394729-17-0; 4-[6-Amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile; 5-Bromo-N4-(4-cyanophenyl)-6-aminopyrimidine-2,4-diamine 4-(3,5-dimethyl-4-cyanophenoxy) derivative
EINECS	Contact for details

Quality Control

Our 4-[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl]Oxy-3,5-Dimethyl-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.