Description

N-(4-(Acetylamino)Phenyl)-2,2,2-Trifluoroacetamide is a specialized trifluoroacetamide derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the trifluoroacetyl group, a key moiety that can significantly alter the physicochemical and metabolic properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoroacetyl-protected amine functionalities.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers with unique surface properties or chemical resistance.
• Chemical Biology Probe Development: Useful for labeling or modifying biomolecules to study protein function and interaction pathways.

Basic Information

Product Name	N-(4-(Acetylamino)Phenyl)-2,2,2-Trifluoroacetamide
CAS No.	392695-18-0
Molecular Formula	C10H9F3N2O2
Molecular Weight	246.19 g/mol
Synonyms	N-[4-(Acetylamino)phenyl]-2,2,2-trifluoroacetamide; 4'-Acetamido-2,2,2-trifluoroacetanilide; 2,2,2-Trifluoro-N-[4-(acetylamino)phenyl]acetamide; N-(4-Acetamidophenyl)-2,2,2-trifluoroacetamide; 1-[4-(2,2,2-Trifluoroacetamido)phenyl]acetamide; p-(2,2,2-Trifluoroacetamido)acetanilide
EINECS	Contact for details

Quality Control

Our N-(4-(Acetylamino)Phenyl)-2,2,2-Trifluoroacetamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.