Description

D-Isovaline, 4-Hydroxy-n-Methyl- (9Ci) is a specialized, non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate for the development of novel bioactive molecules and fine chemicals. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in peptide mimetics, metabolic studies, and the synthesis of complex organic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and mimetics to study structure-activity relationships and improve drug stability.
• Biochemical Tool Compound: Employed in metabolic pathway studies and as a probe in neuroscience research due to its structural similarity to neurotransmitter modulators.
• Fine Chemical Synthesis: Serves as a specialized building block for the production of complex, high-value organic molecules in custom synthesis projects.
• Asymmetric Catalysis: May be used as a precursor or ligand in chiral catalysis for the synthesis of enantiomerically pure compounds.
• Academic & Industrial R&D: A valuable material for fundamental chemical research in universities and corporate R&D laboratories exploring new synthetic methodologies.

Basic Information

Product Name	D-Isovaline, 4-Hydroxy-n-Methyl- (9Ci)
CAS No.	391870-63-6
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	4-Hydroxy-N-methyl-D-isovaline; (2R)-2-Amino-2-ethyl-3-hydroxy-N-methylbutanamide; D-4-Hydroxy-N-methylisovaline; 2-Ethyl-3-hydroxy-N-methyl-D-alanine; (R)-2-Amino-2-ethyl-3-hydroxy-N-methylbutyramide; 391870-63-6; 4-Hydroxy-N-methyl-D-isovaline (9CI)
EINECS	Contact for details

Quality Control

Our D-Isovaline, 4-Hydroxy-n-Methyl- (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity (typically ≥95% to ≥98% by HPLC), and specific test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.