Description

Mono-Fmoc Ethylene Diamine Hydrochloride is a key protected diamine building block extensively used in solid-phase peptide synthesis (SPPS). This compound is critical for introducing a selectively protected ethylenediamine moiety into peptide chains, enabling the creation of complex molecular architectures. It is an essential reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a fundamental building block for introducing a selectively protected amine handle.
• Pharmaceutical Intermediates: Synthesis of active pharmaceutical ingredients (APIs) for peptide drugs, including hormone analogs and enzyme inhibitors.
• Linker Chemistry: Used in the construction of cleavable linkers for combinatorial chemistry and bioconjugation applications.
• Dendrimer and Polymer Synthesis: Serves as a branching unit or functional monomer for creating advanced polymeric materials.
• Proteomics Research: Preparation of affinity tags, cross-linking agents, and other specialized reagents for protein study.
• Chemical Biology Probes: Development of fluorescent or bioactive probes for cellular imaging and target engagement studies.

Basic Information

Product Name	Mono-Fmoc Ethylene Diamine Hydrochloride
CAS No.	391624-46-7
Molecular Formula	C₁₇H₁₉N₂O₂·HCl
Molecular Weight	328.81 g/mol
Synonyms	N-(9-Fluorenylmethoxycarbonyl)ethylenediamine hydrochloride; N-Fmoc-ethylenediamine hydrochloride; 2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethylamine hydrochloride; 1-Amino-2-(Fmoc-amino)ethane hydrochloride; Fmoc-NH-CH₂-CH₂-NH₂·HCl; Nα-Fmoc-1,2-ethanediamine hydrochloride; N-(2-Aminoethyl)-9H-fluoren-9-ylmethoxycarboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our Mono-Fmoc Ethylene Diamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.