Description

Fa-Gly-Phe-Leu-Oh CAS NO 390766-88-8 is a synthetic tetrapeptide derivative, featuring a formyl (Fa) group at the N-terminus. This compound is a valuable building block and research tool in peptide chemistry and medicinal research, enabling the study of peptide structure-activity relationships and enzyme-substrate interactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, biochemical assay development, and as a precursor for more complex peptide synthesis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and optimization of novel peptide-based therapeutics.
• Biochemical Assays: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases and peptidases, to investigate catalytic mechanisms.
• Peptide Library Construction: Acts as a building block in combinatorial chemistry for generating diverse peptide libraries to screen for biological activity.
• Structure-Activity Relationship (SAR) Studies: The formyl group and specific amino acid sequence (Gly-Phe-Leu) make it a useful model compound for probing the importance of terminal modifications and side-chain interactions.
• Academic Research: Employed in university and institutional labs for fundamental research in biochemistry, molecular biology, and chemical biology.
• Process Development: Used in scaling up and optimizing synthetic routes for related peptide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Fa-Gly-Phe-Leu-Oh
CAS No.	390766-88-8
Molecular Formula	C24H34N4O6
Molecular Weight	474.55 g/mol
Synonyms	N-Formyl-glycyl-L-phenylalanyl-L-leucine; For-Gly-Phe-Leu-OH; N-Formyl-Gly-Phe-Leu; Formyl-Glycine-Phenylalanine-Leucine; F-G-F-L; N-Formyl-Gly-Phe-Leu-OH; Tetrapeptide Fa-Gly-Phe-Leu; L-Leucine, N-formylglycyl-L-phenylalanyl-
EINECS	Contact for details

Quality Control

Our Fa-Gly-Phe-Leu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all specified parameters to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.