Description

(S)-α-Amino-2,3,4,5,6,7-Hexahydro-2,4-Dioxo-1H-Cyclopentapyrimidine-1-Propanoic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a fused cyclopentapyrimidine dione core. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with precise stereochemistry for advanced research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutics, particularly enzyme inhibitors and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Protease Inhibitor Research: Serves as a core structural motif for designing and synthesizing novel inhibitors for proteolytic enzymes.
• Peptidomimetic Chemistry: Used to construct conformationally constrained peptide analogs to enhance metabolic stability and bioavailability.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme mechanisms and signal transduction pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Academic & Institutional Research: Supports chemical biology and medicinal chemistry programs in universities and research institutes.

Basic Information

Product Name	(S)-α-Amino-2,3,4,5,6,7-Hexahydro-2,4-Dioxo-1H-Cyclopentapyrimidine-1-Propanoic Acid
CAS No.	389888-02-2
Molecular Formula	C₁₀H₁₃N₃O₄
Molecular Weight	239.23 g/mol
Synonyms	(S)-1-(2-Amino-2-carboxyethyl)-2,4-dioxohexahydro-1H-cyclopenta[d]pyrimidine; (S)-2-Amino-3-(2,4-dioxo-1,2,3,4,5,6,7-hexahydrocyclopenta[d]pyrimidin-1-yl)propanoic acid; (S)-AADCP; (S)-Cyclopentapyrimidine propanoic acid derivative; 1H-Cyclopenta[d]pyrimidine-1-propanoic acid, α-amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-, (S)-; CAS 389888-02-2
EINECS	Contact for details

Quality Control

Our (S)-α-Amino-2,3,4,5,6,7-Hexahydro-2,4-Dioxo-1H-Cyclopentapyrimidine-1-Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and cGMP-grade standards where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.