Description

5-Pyrimidinemethanol, 4-Chloro- (9Ci) is a versatile pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its functionalized structure, which serves as a critical intermediate for constructing more complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), nucleoside analogs, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer drug candidates, particularly those targeting nucleotide metabolism.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides that utilize pyrimidine cores for enhanced activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Nucleoside Analog Preparation: Employed in the modification of nucleoside structures to develop probes or potential therapeutic agents.
• Fine Chemical Manufacturing: Acts as a specialized intermediate in custom synthesis and contract manufacturing for high-value chemical products.

Basic Information

Product Name	5-Pyrimidinemethanol, 4-Chloro- (9Ci)
CAS No.	389799-45-5
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	4-Chloro-5-pyrimidinemethanol; (4-Chloropyrimidin-5-yl)methanol; 4-Chloro-5-(hydroxymethyl)pyrimidine; 5-(Hydroxymethyl)-4-chloropyrimidine; 4-Chloro-5-pyridinemethanol (related); CAS 389799-45-5
EINECS	Contact for details

Quality Control

Every batch of 5-Pyrimidinemethanol, 4-Chloro- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.