Description

2-Chloro-4-[(2,2,2-Trifluoroethyl)-Amino]Pyrimidine-5-Carbonitrile is a high-value pyrimidine derivative and a key synthetic intermediate in modern organic chemistry. This compound matters for its role as a versatile building block in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used as a building block for developing new herbicides and fungicides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Material Science: Potential intermediate for the synthesis of specialty polymers and advanced organic electronic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies and novel reaction development.

Basic Information

Product Name	2-Chloro-4-[(2,2,2-Trifluoroethyl)-Amino]Pyrimidine-5-Carbonitrile
CAS No.	389606-51-3
Molecular Formula	C7H4ClF3N4
Molecular Weight	236.58 g/mol
Synonyms	2-Chloro-4-[(2,2,2-trifluoroethyl)amino]pyrimidine-5-carbonitrile; 4-[(2,2,2-Trifluoroethyl)amino]-2-chloropyrimidine-5-carbonitrile; 2-Chloro-4-(2,2,2-trifluoroethylamino)pyrimidine-5-carbonitrile; 5-Cyano-2-chloro-4-[(2,2,2-trifluoroethyl)amino]pyrimidine; 389606-51-3; 2-Chloro-4-(trifluoroethylamino)pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-[(2,2,2-Trifluoroethyl)-Amino]Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.