Description

3-Amino-2-(4-Fluorophenyl)Quinazolin-4(3H)-One is a high-purity, fluorinated quinazolinone derivative, a key heterocyclic scaffold in modern organic synthesis. This compound matters for its role as a versatile and critical pharmaceutical intermediate, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential kinase inhibitors and other biologically active molecules.
• Drug Discovery & Development: Used in medicinal chemistry research for creating and optimizing new chemical entities (NCEs) targeting various diseases.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides or fungicides with enhanced efficacy.
• Chemical Synthesis: Acts as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and custom synthesis projects.

Basic Information

Product Name	3-Amino-2-(4-Fluorophenyl)Quinazolin-4(3H)-One
CAS No.	388106-35-2
Molecular Formula	C14H10FN3O
Molecular Weight	255.25 g/mol
Synonyms	3-Amino-2-(4-fluorophenyl)-4(3H)-quinazolinone; 2-(4-Fluorophenyl)-3-amino-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 3-amino-2-(4-fluorophenyl)-; 388106-35-2; 3-Amino-2-(p-fluorophenyl)quinazolin-4-one; 3-Amino-2-(4'-fluorophenyl)-4(3H)-quinazolinone; 2-(4-Fluorophenyl)-3-aminoquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 3-Amino-2-(4-Fluorophenyl)Quinazolin-4(3H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent quality suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.