Description

5-Pyrimidinecarboxaldehyde, 4-Amino-1,2-Dihydro-1-Methyl-2-Oxo- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating targeted molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require a functionalized pyrimidine core.
• Fine Chemical Synthesis: Serves as a versatile starting material for creating complex heterocyclic compounds used in material science and specialty chemistry.
• Bioconjugate Chemistry: The aldehyde and amino functional groups enable its use in linker technologies for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	5-Pyrimidinecarboxaldehyde, 4-Amino-1,2-Dihydro-1-Methyl-2-Oxo- (9Ci)
CAS No.	387334-40-9
Molecular Formula	C7H7N3O2
Molecular Weight	165.15 g/mol
Synonyms	4-Amino-1-methyl-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde; 4-Amino-1-methyl-2-oxo-1,2-dihydro-5-pyrimidinecarboxaldehyde; 1-Methyl-4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxaldehyde; 5-Formyl-4-amino-1-methyl-2(1H)-pyrimidinone; 4-Amino-1-methyl-2(1H)-pyrimidinone-5-carboxaldehyde; 4-Amino-1-methyluracil-5-carboxaldehyde; 5-Aldehyde-4-amino-1-methyluracil
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxaldehyde, 4-Amino-1,2-Dihydro-1-Methyl-2-Oxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.