Description

Dapk Substrate Peptide CAS NO 386769-53-5 is a specialized synthetic peptide sequence designed as a selective substrate for Death-Associated Protein Kinase (DAPK) activity. This compound is critical for biochemical research and high-throughput screening applications targeting apoptosis and autophagy signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers working in neuroscience, oncology, and cell biology.

Application

• Enzyme Kinetics & Inhibition Studies: Used as a specific substrate to measure DAPK enzyme activity and to screen for potential kinase inhibitors in drug discovery.
• Biochemical Assay Development: Essential for developing and validating in vitro kinase assays, including ELISA, fluorescence polarization (FP), and radiometric formats.
• Apoptosis & Autophagy Research: Facilitates the study of DAPK's role in programmed cell death and cellular self-degradation pathways.
• High-Throughput Screening (HTS): Employed in automated screening platforms to identify novel modulators of DAPK for therapeutic intervention.
• Diagnostic Reagent Component: Can be incorporated into test kits for measuring DAPK activity in clinical research samples.
• Signal Transduction Pathway Analysis: Helps elucidate the complex signaling networks involving DAPK in various disease models.

Basic Information

Product Name	Dapk Substrate Peptide
CAS No.	386769-53-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	DAPK Substrate; Death-Associated Protein Kinase Substrate Peptide; DAPK1 Substrate; Synthetic DAPK Peptide Substrate; Apoptosis-Related Kinase Substrate; DAP-Kinase Activity Probe; Custom Kinase Substrate 386769-53-5
EINECS	Contact for details

Quality Control

Our Dapk Substrate Peptide is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, peptide content, and performance data in standard kinase assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffer or DMSO
Biological Activity	Validated in standard DAPK kinase assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.