Description

Fmoc-Lys(Mca)-Oh is a specialized, protected amino acid derivative used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity building blocks for complex peptide sequences, particularly those involving lysine residues. It is essential for the development of therapeutic peptides, diagnostic agents, and biochemical research tools in the pharmaceutical and biotechnology sectors.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of lysine into peptide chains, especially where orthogonal protection strategies are required.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs targeting various diseases.
• Bioconjugation and Labeling: The Mca (7-methoxycoumarin-4-yl)acetyl group can serve as a fluorescent probe or a handle for further chemical modification.
• Biochemical Research: Employed in studying protein-protein interactions, enzyme substrates, and as a tool compound in molecular biology.
• Combinatorial Chemistry: A valuable reagent for generating diverse peptide libraries for screening and discovery purposes.
• Antibody-Drug Conjugate (ADC) Research: Potential use in the synthesis of peptide linkers for targeted drug delivery systems.

Basic Information

Product Name	Fmoc-Lys(Mca)-Oh
CAS No.	386213-32-7
Molecular Formula	C₃₁H₃₀N₂O₇
Molecular Weight	542.58 g/mol
Synonyms	Fmoc-Lys(Mca)-OH; N-α-Fmoc-N-ε-(7-Methoxycoumarin-4-yl)acetyl-L-lysine; Fmoc-L-lysine(Mca)-OH; N-ε-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-N-α-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine; Fmoc-Lys(Mca)-OH (Mca = 7-Methoxycoumarin-4-yl)acetyl); Fmoc-Lys(7-Methoxycoumarin-4-yl)acetyl)-OH; Fmoc-Lys(Mca)-OH (Peptide Grade)
EINECS	Contact for details

Quality Control

Our Fmoc-Lys(Mca)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.