Description

2(1H)-Pyrimidinone, 3,4-Dihydro-5-Nitro- (9Ci) is a specialized nitro-substituted dihydropyrimidinone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its unique heterocyclic scaffold, which is pivotal for constructing complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require precise building blocks for drug discovery, crop protection agents, and functional materials development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its nitro-heterocyclic structure for enhanced bioactivity.
• Fine Chemical Synthesis: Employed as a versatile building block for creating complex heterocycles, dyes, and ligands for catalysis in custom synthesis projects.
• Academic & R&D: Serves as a critical reagent in medicinal chemistry and organic synthesis research within university laboratories and corporate R&D centers for exploring new chemical spaces.
• Material Science: Investigated for potential use in the development of organic electronic materials and photoactive compounds due to its electron-accepting nitro group.

Basic Information

Product Name	2(1H)-Pyrimidinone, 3,4-Dihydro-5-Nitro- (9Ci)
CAS No.	385437-61-6
Molecular Formula	C4H5N3O3
Molecular Weight	143.10 g/mol
Synonyms	5-Nitro-3,4-dihydro-2(1H)-pyrimidinone; 5-Nitro-3,4-dihydropyrimidin-2(1H)-one; 3,4-Dihydro-5-nitro-2(1H)-pyrimidinone; 5-Nitrodihydrouracil; 385437-61-6; 5-Nitro-DHU; 5-Nitro-1,4,5,6-tetrahydropyrimidin-2-ol
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone, 3,4-Dihydro-5-Nitro- (9Ci) is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality ensures the material meets the high standards required for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.