Description

3-(((4-Amino-5,6-Dimethylthieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)-1H-Pyrazol-5-Ol is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel, targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs, particularly in oncology and other disease areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Used in the construction of potential kinase inhibitor candidates due to its thienopyrimidine core, a privileged structure in this drug class.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in academic and industrial R&D labs.
• Biochemical Tool Compound: May be utilized as a reference standard or probe in biological screening assays to study specific enzymatic pathways.
• Custom Synthesis Building Block: Provides a versatile, functionalized scaffold for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	3-(((4-Amino-5,6-Dimethylthieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)-1H-Pyrazol-5-Ol
CAS No.	385421-11-4
Molecular Formula	C₁₂H₁₂N₆OS₂
Molecular Weight	320.39 g/mol
Synonyms	1H-Pyrazol-5-ol, 3-(((4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)thio)methyl)-; 4-Amino-5,6-dimethyl-2-(((5-hydroxy-1H-pyrazol-3-yl)methyl)thio)thieno[2,3-d]pyrimidine; 385421-11-4; Thieno[2,3-d]pyrimidine derivative; Amino-dimethylthienopyrimidinyl thiomethyl pyrazolol
EINECS	Contact for details

Quality Control

Every batch of 3-(((4-Amino-5,6-Dimethylthieno[2,3-D]Pyrimidin-2-Yl)Thio)Methyl)-1H-Pyrazol-5-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support research and development applications, ensuring identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as HPLC purity, NMR confirmation, and residual solvent levels are available upon request for quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.